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Literature summary extracted from

  • Ikebe, M.; Reardon, S.; Fay, F.S.
    Primary structure required for the inhibition of smooth muscle myosin light chain kinase (1992), FEBS Lett., 312, 245-248.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.18 AKKLSKDRMAAYMARRK synthetic peptide, analog of inhibitory region of myosin light chain kinase Meleagris gallopavo
2.7.11.18 AKKLSKDRMKKYMA synthetic peptide, analog of inhibitory region of myosin light chain kinase Meleagris gallopavo
2.7.11.18 AKKLSKDRMKKYMAAAA synthetic peptide, analog of inhibitory region of myosin light chain kinase Meleagris gallopavo
2.7.11.18 AKKLSKDRMKKYMARR synthetic peptide, analog of inhibitory region of myosin light chain kinase Meleagris gallopavo
2.7.11.18 AKKLSKDRMKKYMARRK synthetic peptide, analog of inhibitory region of myosin light chain kinase Meleagris gallopavo
2.7.11.18 AKKLSKDRMKKYMARRKWQKTG synthetic peptide, analog of inhibitory region of myosin light chain kinase Meleagris gallopavo
2.7.11.18 KDRMKKYMARR synthetic peptide, analog of inhibitory region of myosin light chain kinase Meleagris gallopavo
2.7.11.18 LSKDRMKKYMARRKWQK synthetic peptide, analog of inhibitory region of myosin light chain kinase Meleagris gallopavo
2.7.11.18 additional information structural requirements of autoinhibition of myosin light chain kinase Meleagris gallopavo

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.18 Ca2+
-
 Meleagris gallopavo

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.18 ATP + myosin light chain Meleagris gallopavo
-
 ADP + myosin light chain phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.18 Meleagris gallopavo
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.18 gizzard
-
 Meleagris gallopavo
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.18 ATP + myosin light chain
-
 Meleagris gallopavo ADP + myosin light chain phosphate
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.18 Calmodulin requirement Meleagris gallopavo