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Literature summary extracted from

  • Durante, P.; Raleigh, X.; Gomez, M.E.; Campos, G.; Ryder, E.
    Isozyme analysis of human normal polymorphonuclear leukocyte phosphofructokinase (1995), Biochem. Biophys. Res. Commun., 216, 898-905.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.1.11 D-Glucose 1,6-bisphosphate 0.02 mM, 474% and 360% activation of M- and L-type PFK, respectively Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.11 ATP inhibition of M-type PFK above 0.1 mM Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.11 0.047
-
 D-fructose 6-phosphate pH 7.1, 25°C, M-type PFK Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.1.11 74250
-
 x * 74250, L-type PFK Homo sapiens
2.7.1.11 79500
-
 x * 79500, M-type PFK Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.11 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.11 QAE-Sepharose, partially purified Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.11 leukocyte polymorphonuclear leukocytes, predominance of L-type PFK Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.11 ATP + D-fructose 6-phosphate
-
 Homo sapiens ADP + D-fructose 1,6-bisphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.1.11 ? x * 74250, L-type PFK Homo sapiens
2.7.1.11 ? x + 82000, C-type PFK Homo sapiens
2.7.1.11 ? x * 79500, M-type PFK Homo sapiens