EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.1 | 2,3-diphosphoglycerate | hexokinase III | Sus scrofa | |
2.7.1.1 | 2-phosphoglycerate | hexokinase III | Sus scrofa | |
2.7.1.1 | 3-phosphoglycerate | hexokinase III | Sus scrofa | |
2.7.1.1 | ADP | hexokinase III | Sus scrofa | |
2.7.1.1 | ATP | ATP4-; hexokinase III; uncomplexed, competitive to MgATP2-, erythrocyte enzyme | Sus scrofa | |
2.7.1.1 | D-fructose 1,6-diphosphate | hexokinase III | Sus scrofa | |
2.7.1.1 | D-fructose 6-phosphate | hexokinase III | Sus scrofa | |
2.7.1.1 | D-glucose | higher than 0.4 mM; inhibits hexokinase III | Sus scrofa | |
2.7.1.1 | D-glucose 1,6-diphosphate | hexokinase III | Sus scrofa | |
2.7.1.1 | D-glucose 6-phosphate | hexokinase III, poor inhibitor, not relieved by phosphate | Sus scrofa | |
2.7.1.1 | dihydroxyacetonephosphate | hexokinase III | Sus scrofa | |
2.7.1.1 | Mg2+ | competitive to MgATP2-; uncomplexed | Sus scrofa | |
2.7.1.1 | additional information | not inhibited by glyceraldehyde 3-phosphate, pyruvate, lactate | Sus scrofa | |
2.7.1.1 | phosphate | hexokinase III | Sus scrofa | |
2.7.1.1 | phosphoenolpyruvate | hexokinase III | Sus scrofa |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.1 | 0.5 | - |
ATP | hexokinase III, at 30°C, pH 8.1 | Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.1 | D-glucose + ATP | Sus scrofa | the presence of type III hexokinase enables the adult pig erythrocytes to metabolize low but appreciable amounts of glucose | D-glucose 6-phosphate + ADP | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.1 | Sus scrofa | - |
2 enzyme forms: hexokinase type II and type III | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.1 | erythrocyte | hexokinase types II and III, hexokinase III is the predominant form in adult pig erythrocytes, hexokinase II in newborn pig erythrocytes | Sus scrofa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.1 | D-glucose + ATP | - |
Sus scrofa | ADP + D-glucose 6-phosphate | - |
? | |
2.7.1.1 | D-glucose + ATP | the presence of type III hexokinase enables the adult pig erythrocytes to metabolize low but appreciable amounts of glucose | Sus scrofa | D-glucose 6-phosphate + ADP | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.7.1.1 | 30 | - |
assay at | Sus scrofa |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.7.1.1 | 7.2 | - |
assay at | Sus scrofa |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.1 | ATP | - |
Sus scrofa |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.1 | 0.04 | - |
D-glucose 1,6-diphosphate | hexokinase III, at 30°C, pH 7.2 | Sus scrofa | |
2.7.1.1 | 0.12 | - |
D-glucose 6-phosphate | hexokinase III, at 30°C, pH 7.2 | Sus scrofa | |
2.7.1.1 | 0.5 | - |
ADP | hexokinase III, at 30°C, pH 7.2 | Sus scrofa | |
2.7.1.1 | 0.5 | - |
D-fructose 6-phosphate | hexokinase III, at 30°C, pH 7.2 | Sus scrofa | |
2.7.1.1 | 0.5 | - |
ATP | uncomplexed ATP4-, hexokinase III, at 30°C, pH 7.2 | Sus scrofa | |
2.7.1.1 | 2.5 | - |
D-fructose 1,6-diphosphate | hexokinase III, at 30°C, pH 7.2 | Sus scrofa | |
2.7.1.1 | 2.5 | - |
dihydroxyacetonephosphate | hexokinase III, at 30°C, pH 7.2 | Sus scrofa | |
2.7.1.1 | 5 | - |
2,3-diphosphoglycerate | hexokinase III, at 30°C, pH 7.2 | Sus scrofa | |
2.7.1.1 | 7.8 | - |
phosphate | hexokinase III, at 30°C, pH 7.2 | Sus scrofa | |
2.7.1.1 | 8 | - |
phosphoenolpyruvate | hexokinase III, at 30°C, pH 7.2 | Sus scrofa | |
2.7.1.1 | 12 | - |
3-phosphoglycerate | hexokinase III, at 30°C, pH 7.2 | Sus scrofa | |
2.7.1.1 | 13 | - |
2-phosphoglycerate | hexokinase III, at 30°C, pH 7.2 | Sus scrofa | |
2.7.1.1 | 30 | - |
Mg2+ | uncomplexed, hexokinase III, at 30°C, pH 7.2 | Sus scrofa |