EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.1 | D-mannose | competitive to D-glucose; glucokinase | Saccharomyces cerevisiae | |
2.7.1.1 | D-xylose | irreversible inactivation of the 3 isoenzymes, hexokinase PI inactivation requires ATP, hexokinase PII is inactivated by D-xylose without ATP, glucokinase is protected by ATP, competitive inhibitor of hexokinase PI and glucokinase, non-competitive inhibitor of hexokinase PII | Saccharomyces cerevisiae |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.1 | additional information | - |
additional information | - |
Saccharomyces cerevisiae | |
2.7.1.1 | 0.04 | - |
D-glucose | glucokinase | Saccharomyces cerevisiae | |
2.7.1.1 | 0.04 | - |
D-mannose | glucokinase | Saccharomyces cerevisiae | |
2.7.1.1 | 0.12 | - |
D-glucose | hexokinases PI and PII | Saccharomyces cerevisiae | |
2.7.1.1 | 0.33 | - |
D-fructose | hexokinases PI and PII | Saccharomyces cerevisiae |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.1 | additional information | Saccharomyces cerevisiae | hexokinase PI is a constitutive enzyme, hexokinase PII and glucokinase are regulated by the carbon source used | ? | - |
? | |
2.7.1.1 | additional information | Saccharomyces cerevisiae G-517 / CECT 1317 | hexokinase PI is a constitutive enzyme, hexokinase PII and glucokinase are regulated by the carbon source used | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.1 | Saccharomyces cerevisiae | - |
3 isoenzymes PI, PII and glucokinase | - |
2.7.1.1 | Saccharomyces cerevisiae G-517 / CECT 1317 | - |
3 isoenzymes PI, PII and glucokinase | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.1.1 | 3 isoenzymes PI, PII and glucokinase, partial | Saccharomyces cerevisiae |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.1 | D-fructose + ATP | hexokinases PI and PII phosphorylate fructose 2.5 and 1.5times faster than glucose, glucokinase: very low or no activity | Saccharomyces cerevisiae | ADP + D-fructose 6-phosphate | - |
? | |
2.7.1.1 | D-fructose + ATP | hexokinases PI and PII phosphorylate fructose 2.5 and 1.5times faster than glucose, glucokinase: very low or no activity | Saccharomyces cerevisiae G-517 / CECT 1317 | ADP + D-fructose 6-phosphate | - |
? | |
2.7.1.1 | D-glucose + ATP | - |
Saccharomyces cerevisiae | ADP + D-glucose 6-phosphate | - |
? | |
2.7.1.1 | D-glucose + ATP | - |
Saccharomyces cerevisiae G-517 / CECT 1317 | ADP + D-glucose 6-phosphate | - |
? | |
2.7.1.1 | D-mannose + ATP | glucokinase | Saccharomyces cerevisiae | ADP + D-mannose 6-phosphate | - |
? | |
2.7.1.1 | D-mannose + ATP | glucokinase | Saccharomyces cerevisiae G-517 / CECT 1317 | ADP + D-mannose 6-phosphate | - |
? | |
2.7.1.1 | additional information | glucokinase: not: fructose, galactose, sorbose, rhamnose, arabinose, mannitol, sorbitol, ribose | Saccharomyces cerevisiae | ? | - |
? | |
2.7.1.1 | additional information | hexokinase PI is a constitutive enzyme, hexokinase PII and glucokinase are regulated by the carbon source used | Saccharomyces cerevisiae | ? | - |
? | |
2.7.1.1 | additional information | glucokinase: not: fructose, galactose, sorbose, rhamnose, arabinose, mannitol, sorbitol, ribose | Saccharomyces cerevisiae G-517 / CECT 1317 | ? | - |
? | |
2.7.1.1 | additional information | hexokinase PI is a constitutive enzyme, hexokinase PII and glucokinase are regulated by the carbon source used | Saccharomyces cerevisiae G-517 / CECT 1317 | ? | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.7.1.1 | 25 | - |
assay at | Saccharomyces cerevisiae |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.1 | ATP | - |
Saccharomyces cerevisiae |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.1 | 0.06 | - |
D-mannose | glucokinase | Saccharomyces cerevisiae | |
2.7.1.1 | 0.85 | - |
D-xylose | glucokinase | Saccharomyces cerevisiae | |
2.7.1.1 | 25 | - |
D-xylose | hexokinase PI | Saccharomyces cerevisiae | |
2.7.1.1 | 80 | - |
D-xylose | hexokinase PII | Saccharomyces cerevisiae |