EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.6.1.42 | 4-methyl-2-oxopentanoate | - |
Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.6.1.42 | 0.07 | - |
(R,S)-3-methyl-2-oxopentanoate | pH 8.3, 25°C | Rattus norvegicus | |
2.6.1.42 | 0.11 | - |
3-methyl-2-oxobutanoate | pH 8.3, 25°C | Rattus norvegicus | |
2.6.1.42 | 0.14 | - |
4-methyl-2-oxopentanoate | pH 8.3, 25°C | Rattus norvegicus | |
2.6.1.42 | 2.45 | - |
L-glutamate | pH 8.3, 25°C, (R,S)-3-methyl-2-oxopentanoate as amino group acceptor | Rattus norvegicus | |
2.6.1.42 | 3.6 | - |
L-glutamate | pH 8.3, 25°C, 3-methyl-2-oxobutanoate as amino group acceptor | Rattus norvegicus | |
2.6.1.42 | 6.65 | - |
L-glutamate | pH 8.3, 25°C, 4-methyl-2-oxopentanoate as amino group acceptor | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.6.1.42 | L-leucine + 2-oxoglutarate | Rattus norvegicus | - |
4-methyl-2-oxopentanoate + L-glutamate | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.6.1.42 | Bos taurus | - |
bovine | - |
2.6.1.42 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.6.1.42 | partially | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.6.1.42 | aorta | endothelial cells | Bos taurus | - |
2.6.1.42 | heart | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.6.1.42 | L-leucine + 2-oxoglutarate | - |
Rattus norvegicus | 4-methyl-2-oxopentanoate + L-glutamate | - |
r | |
2.6.1.42 | L-leucine + 4-methyl-2-oxopentanoate | - |
Rattus norvegicus | 4-methyl-2-oxopentanoate + L-leucine | - |
r |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.6.1.42 | BCAA-AT | - |
Rattus norvegicus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.6.1.42 | 8.2 | - |
- |
Rattus norvegicus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
2.6.1.42 | 7 | 9 | - |
Rattus norvegicus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.6.1.42 | 2.1 | - |
4-methyl-2-oxopentanoate | pH 8.3, 25°C | Rattus norvegicus |