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Literature summary extracted from

  • Robinson, N.E.; de Vries, T.; Davis, R.E.; Stults, C.L.M.; Watson, S.R.; van den Eijnden, D.H.; Macher, B.A.
    Expression of fucosylated antigens and alpha1,3 fucosyltransferases in human leukemia cell lines (1994), Glycobiology, 4, 317-326.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.152 NEM activity in HL-60 cells is essentially unaffected. The RPMI 8226 enzyme activity is significantly inhibited Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.152 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.152 CCRF-CEM cell
-
Homo sapiens
-
2.4.1.152 HL-60 cell
-
Homo sapiens
-
2.4.1.152 K-562 cell
-
Homo sapiens
-
2.4.1.152 KG-1 cell
-
Homo sapiens
-
2.4.1.152 MOLT-4 cell
-
Homo sapiens
-
2.4.1.152 additional information no activity detected in Daudi, Raji and Reh leukemia cells Homo sapiens
-
2.4.1.152 RPMI-8226 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.152 GDP-L-fucose + Fucalpha(1,2)Galbeta(1,4)GlcNAcbeta(CH2)8COOMe
-
Homo sapiens GDP + Fucalpha(1,2)Galbeta(1,4)(Fucalpha(1,3))GlcNAcbeta(CH2)8COOMe
-
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