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Literature summary extracted from

  • Sherwood, A.L.; Greene, T.G.; Holmes, E.H.
    Stable expression of a cDNA encoding a human beta1 -> 3galactosyltransferase responsible for lacto-series type 1 core chain synthesis in non-expressing cells: variation in the nature of cell surface antigens expressed (1992), J. Cell. Biochem., 50, 165-177.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.179 Triton CF-54
-
 Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.179 functional expression in HCT-15 cells Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-glycolipid Homo sapiens associated with biosynthesis of type 1 lactoseries core chain carbohydrate structure UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-glycolipid
-
 ?
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-glycolipid Homo sapiens involved in elongation of oligosaccharide chains in glycolipids UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-glycolipid
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.179 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.179 Colo-205 cell colonic adenocarcino cell line Homo sapiens
-
2.4.1.179 additional information no activity in normal HCT-15 cells, human colonic adenocarcinoma cell line Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.179 0.00013
-
 recombinant in HCT-15 cells Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-glycolipid associated with biosynthesis of type 1 lactoseries core chain carbohydrate structure Homo sapiens UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-glycolipid
-
 ?
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-glycolipid involved in elongation of oligosaccharide chains in glycolipids Homo sapiens UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-glycolipid
-
 ?
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-R
-
 Homo sapiens UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-R
-
 ?
2.4.1.179 UDP-galactose + lactotriaosylceramide
-
 Homo sapiens UDP + lactotetraosylceramide
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.179 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.179 7
-
 Hepes buffer Homo sapiens
2.4.1.179 7
-
 assay at Homo sapiens