Literature summary extracted from
DeAngelis, P.L.; Padgett-McCue, A.J.
Identification and molecular cloning of a chondroitin synthase from Pasteurella multocida type F (2000), J. Biol. Chem., 275, 24124-24129.
Cloned(Commentary)
EC Number |
Cloned (Comment) |
Organism |
---|
2.4.1.175 |
DNA sequence determination, expression in Escherichia coli of amino acid residues 1-704 of total 965 as soluble functional protein |
Pasteurella multocida |
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
2.4.1.175 |
Pasteurella multocida |
Q9CMP0 |
type F |
- |
Substrates and Products (Substrate)
EC Number |
Substrates |
Comment Substrates |
Organism |
Products |
Comment (Products) |
Rev. |
Reac. |
---|
2.4.1.175 |
UDP-N-acetyl-D-galactosamine + chondroitin oligosaccharide |
high specificity for sugar donor substrates |
Pasteurella multocida |
UDP + N-acetyl-D-galactosaminyl chondroitin oligosaccharide |
transfer in beta-1,4-linkage |
? |
|
Synonyms
EC Number |
Synonyms |
Comment |
Organism |
---|
2.4.1.175 |
More |
the human form of this enzyme is a bifunctional glycosyltransferase, which also has the 3-beta-glucuronosyltransferase, EC 2.4.1.226, activity required for the synthesis of the chondroitin sulfate disaccharide repeats. Similar chondroitin synthase co-polymerases can be found in Pasteurella multocida and Escherichia coli. |
Pasteurella multocida |
2.4.1.175 |
More |
the enzyme also has the 3-beta-glucuronosyltransferase, EC 2.4.1.226, activity |
Pasteurella multocida |