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Literature summary extracted from

  • Guo, H.B.; Jiang, A.L.; Ju, T.Z.; Chen, H.L.
    Opposing changes in N-acetylglucosaminyltransferase-V and -III during the cell cycle and all-trans retinoic acid treatment of hepatocarcinoma cell line (2000), Biochim. Biophys. Acta, 1495, 297-307.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.144 all-trans retinoic acid activation Homo sapiens
2.4.1.144 additional information not affected by cAMP Homo sapiens
2.4.1.144 Triton X-100
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.144 Golgi apparatus
-
 Homo sapiens 5794
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.144 Mn2+
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.144 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.144 hepatoma cell 7721 cells, activity during cell-cycle Homo sapiens
-
2.4.1.144 hepatoma cell line 7721 cell Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.144 0.0000025
-
 hepatoma cell line 7721 Homo sapiens
2.4.1.144 0.000004
-
 about, hepatoma cell line 7721, all-trans retinoic acid treated Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.144 UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R
-
 Homo sapiens UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-(N-acetyl-beta-D-glucosaminyl-1,4)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R incorporates a N-acetylglucosamine residue in beta-1,4-linkage to beta-linked mannosyl, i.e. bisecting N-acetylglucosamine ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.144 beta-D-mannoside beta-1,4-N-acetylglucosaminyltransferase
-
 Homo sapiens
2.4.1.144 GnT-III
-
 Homo sapiens
2.4.1.144 N-acetyl-glucosaminyltransferase III
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.144 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.144 6.3
-
 assay at Homo sapiens