Literature summary extracted from

Flaks, J.G.; Erwin, M.J.; Buchanan, J.M.
Biosynthesis of the purines. XVI. The synthesis of adenosine 5'-phosphate and 5-amino-4-imidazolecarboxamide ribotide by a nucleotide pyrophosphorylase (1957), J. Biol. Chem., 228, 201-213.

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
2.4.2.7	Mg2+	required	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.2.7	Bos taurus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
2.4.2.7	-	Bos taurus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.4.2.7	liver	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.2.7	5-amino-4-imidazolecarboxamide + 5-phospho-alpha-D-ribose 1-diphosphate	-	Bos taurus	5-amino-4-imidazolecarboxamide ribotide + diphosphate	-	?
2.4.2.7	adenine + 5-phospho-alpha-D-ribose 1-diphosphate	equilibrium lies far in the direction of nucleotide synthesis	Bos taurus	AMP + diphosphate	-	?

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Release 2023.1 (January 2023)