BRENDA - Enzyme Database

Kinetic mechanisms of two NAD:arginine ADP-ribosyltransferases: the soluble, salt-stimulated transferase from turkey erythrocytes and choleragen, a toxin from Vibrio cholerae

Osborne, J.C.; Stanley, S.J.; Moss, J.; Biochemistry 24, 5235-5240 (1985)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.4.2.31
nicotinamide
-
Meleagris gallopavo
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.4.2.31
0.007
-
NAD+
-
Meleagris gallopavo
2.4.2.31
0.26
-
1-(4-aminobutyl)guanidine
-
Meleagris gallopavo
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.4.2.31
Meleagris gallopavo
-
-
-
Reaction
EC Number
Reaction
Commentary
Organism
2.4.2.31
NAD+ + protein L-arginine = nicotinamide + Nomega-(ADP-D-ribosyl)-protein-L-arginine
rapid equilibrium random sequential mechanism
Meleagris gallopavo
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.4.2.31
erythrocyte
-
Meleagris gallopavo
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.2.31
agmatine + NAD+
-
638101
Meleagris gallopavo
nicotinamide + ?
-
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
2.4.2.31
NAD+
-
Meleagris gallopavo
Ki Value [mM]
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
2.4.2.31
0.37
-
nicotinamide
-
Meleagris gallopavo
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
2.4.2.31
NAD+
-
Meleagris gallopavo
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.4.2.31
nicotinamide
-
Meleagris gallopavo
Ki Value [mM] (protein specific)
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
2.4.2.31
0.37
-
nicotinamide
-
Meleagris gallopavo
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.4.2.31
0.007
-
NAD+
-
Meleagris gallopavo
2.4.2.31
0.26
-
1-(4-aminobutyl)guanidine
-
Meleagris gallopavo
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.4.2.31
erythrocyte
-
Meleagris gallopavo
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.2.31
agmatine + NAD+
-
638101
Meleagris gallopavo
nicotinamide + ?
-
-
-
?