Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Aktories, K.; Roesener, S.; Blaschke, U.; Chhatwal, G.S.
    Botulinum ADP-ribosyltransferase C3. Purification of the enzyme and characterization of the ADP-ribosylation reaction in platelet membranes (1988), Eur. J. Biochem., 172, 445-450.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.2.30 GDP increases activity in absence of Mg2+ Clostridium botulinum
2.4.2.30 GTP increases activity in absence of Mg2+ Clostridium botulinum
2.4.2.30 GTP(gammaS) increases activity in absence of Mg2+ Clostridium botulinum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.2.30 0.002
-
 NAD+
-
 Clostridium botulinum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.2.30 25000
-
 x * 25000, SDS-PAGE Clostridium botulinum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.2.30 additional information Clostridium botulinum the enzyme modifies eukaryotic 21000-24000 Da GTP-binding proteins ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.30 Clostridium botulinum
-
 type c
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.2.30
-
 Clostridium botulinum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.30 additional information the enzyme modifies eukaryotic 21000-24000 Da GTP-binding proteins Clostridium botulinum ?
-
 ?
2.4.2.30 NAD+ + (ADP-D-ribosyl)n-acceptor poly(ADP-ribosyl)ation of 21000-24000 Da platelet membrane proteins Clostridium botulinum nicotinamide + (ADP-D-ribosyl)n+1-acceptor
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.2.30 ? x * 25000, SDS-PAGE Clostridium botulinum