EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.3.4.21 | 5-phospho-alpha-D-ribose 1-diphosphate | at high concentrations | Saccharomyces cerevisiae | |
6.3.4.21 | nicotinate mononucleotide | - |
Saccharomyces cerevisiae |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.3.4.21 | 0.023 | - |
nicotinate | - |
Saccharomyces cerevisiae | |
6.3.4.21 | 0.024 | - |
5-phospho-alpha-D-ribose 1-diphosphate | - |
Saccharomyces cerevisiae | |
6.3.4.21 | 0.07 | - |
ATP | - |
Saccharomyces cerevisiae |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
6.3.4.21 | 45000 | - |
SDS-PAGE in the presence and absence of mercaptoethanol | Saccharomyces cerevisiae |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.4.21 | nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O | Saccharomyces cerevisiae | - |
beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.4.21 | Saccharomyces cerevisiae | - |
Budweiser brand | - |
6.3.4.21 | Saccharomyces cerevisiae | - |
bakers´yeast | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
6.3.4.21 | extraction, fractionation chromatography on phosphocellulose, hydroxyapatite, blue Sephadex and DEAE-cellulose | Saccharomyces cerevisiae |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
6.3.4.21 | nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate | ordered ping pong kinetic mechanism | Saccharomyces cerevisiae |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.4.21 | additional information | ATP and phosphoribose diphosphate compete for ATP-binding site | Saccharomyces cerevisiae | ? | - |
? | |
6.3.4.21 | additional information | ATPase activity in the presence of either product and in the absence of phosphoribose diphosphate | Saccharomyces cerevisiae | ? | - |
? | |
6.3.4.21 | nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O | - |
Saccharomyces cerevisiae | beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
6.3.4.21 | additional information | - |
pI: 6.9 | Saccharomyces cerevisiae |