Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Kim, D.H.; Lees, W.J.; Walsh, C.T.
    Stereochemical analysis of the tetrahedral adduct formed at the active site of UDP-GlcNAc enolpyruvyl transferase from the pseudosubstrates, (E)- and (Z)-3-fluorophosphoenolpyruvate, in D2O (1995), J. Am. Chem. Soc., 117, 6380-6381.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.7 (E)-3-fluorophosphoenolpyruvate pseudosubstrate, formation of a tetrahedral intermediate in the reaction pathway, investigation of chirality of the intermediate stereospecifically formed at the active site in D2O Escherichia coli
2.5.1.7 (Z)-3-fluorophosphoenolpyruvate pseudosubstrate, formation of a tetrahedral intermediate in the reaction pathway, investigation of chirality of the intermediate stereospecifically formed at the active site in D2O Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.7 Escherichia coli
-
 MurZ
-
2.5.1.7 Escherichia coli MurZ
-
 MurZ
-

Reaction

EC Number Reaction Comment Organism Reaction ID
2.5.1.7 phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine the addition step proceeds with protonation of C-3 of phosphoenolpyruvate from the 2-si face Escherichia coli
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.7 phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine
-
 Escherichia coli phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine
-
 ?
2.5.1.7 phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine
-
 Escherichia coli MurZ phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.7 UDP-GlcNAc enolpyruvyl transferase
-
 Escherichia coli