Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Mitsuda, H.; Nakajima, K.; Nadamoto, T.; Yamada, Y.
    Riboflavin synthetase from Eremothecium ashbyii and a salvage pathway of the by-product in the enzyme reaction (1980), Methods Enzymol., 66, 307-323.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.5.1.9 diacetyl activates Eremothecium ashbyi

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.9 6,7-dimethyl-8-ribityllumazine + 6,7-dimethyl-8-ribityllumazine Eremothecium ashbyi biosynthetic pathway riboflavin + 4-(1'-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
-
 ?
2.5.1.9 additional information Eremothecium ashbyi salvage cycle for the by-product of the reaction is involved in the de novo synthesis of riboflavin ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.9 Eremothecium ashbyi
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.9
-
 Eremothecium ashbyi

Reaction

EC Number Reaction Comment Organism Reaction ID
2.5.1.9 2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine reaction mechanism Eremothecium ashbyi
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.9 mycelium
-
 Eremothecium ashbyi
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.5.1.9 additional information
-
 various estimation methods Eremothecium ashbyi
2.5.1.9 0.16
-
 purified enzyme Eremothecium ashbyi

Storage Stability

EC Number Storage Stability Organism
2.5.1.9 frozen, mycelium, several months without loss of activity Eremothecium ashbyi

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.9 6,7-dimethyl-8-ribityllumazine + 6,7-dimethyl-8-ribityllumazine
-
 Eremothecium ashbyi riboflavin + 4-(1'-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
-
 ?
2.5.1.9 6,7-dimethyl-8-ribityllumazine + 6,7-dimethyl-8-ribityllumazine biosynthetic pathway Eremothecium ashbyi riboflavin + 4-(1'-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
-
 ?
2.5.1.9 additional information
-
 Eremothecium ashbyi ?
-
 ?
2.5.1.9 additional information salvage cycle for the by-product of the reaction is involved in the de novo synthesis of riboflavin Eremothecium ashbyi ?
-
 ?