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Literature summary extracted from

  • Shigeta, S.; Winter, H.C.; Goldstein, I.J.
    alpha-(2->3)- and alpha-(2->6)-Sialyltransferase activities present in three variants of Ehrlich tumor cells: identification of the products derived from N-acetyllactosamine and beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->O)-Bn (1994), Carbohydr. Res., 264, 111-121.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.3.1 Golgi apparatus
-
 Mus musculus 5794
-
2.4.3.1 membrane
-
 Mus musculus 16020
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.1 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.1 Ehrlich ascites carcinoma cell high activity in cells grown in tissue culture or adherent to extracellular matrices, low activity in cells not adherent nor grown in tissue culture Mus musculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.3.1 0.0000008
-
 Ehrlich ascite carcinoma cells, adherent or from tissue culture Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.1 CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine i.e. N-acetyllactosamine Mus musculus CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R sialic acid is linked to C-6 of the galactose residue Mus musculus CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + lacto-N-neotetraose
-
 Mus musculus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.3.1 37
-
 assay at Mus musculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.3.1 6.5
-
 assay at Mus musculus