EC Number | Cloned (Comment) | Organism |
---|---|---|
2.6.1.7 | transient expression in HEK-293 cells | Rattus norvegicus |
2.6.1.64 | cDNA clone encoding KAT/GTK, transfection of HEK-293 cells | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.6.1.7 | 0.096 | - |
2-oxoglutarate | pH 8.0, 37°C, recombinant mitochondrial enzyme | Rattus norvegicus | |
2.6.1.7 | 1.63 | - |
pyruvate | pH 8.0, 37°C, recombinant mitochondrial enzyme | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.6.1.7 | mitochondrion | cDNA encodes for a kynurenine aminotransferase that is identical to a soluble form but carries an additional stretch of 32 amino acids resembling a mitochondrial import sequence | Rattus norvegicus | 5739 | - |
2.6.1.64 | cytosol | - |
Rattus norvegicus | 5829 | - |
2.6.1.64 | mitochondrion | - |
Rattus norvegicus | 5739 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.6.1.7 | Rattus norvegicus | Q08415 | brain KAT I | - |
2.6.1.64 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.6.1.7 | brain | - |
Rattus norvegicus | - |
2.6.1.64 | brain | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.6.1.7 | L-kynurenine + 2-oxoglutarate | enzyme has both kynurenine aminotransferase and glutamine transaminase K activity | Rattus norvegicus | kynurenic acid + L-glutamate + H2O | - |
? | |
2.6.1.7 | L-kynurenine + pyruvate | - |
Rattus norvegicus | kynurenic acid + L-alanine + H2O | - |
? | |
2.6.1.64 | additional information | cysteine S-conjugate beta-lyase activity, identical with kynurenine pyruvate aminotransferase | Rattus norvegicus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.6.1.7 | KAT | - |
Rattus norvegicus |
2.6.1.64 | EC 2.6.1.14 | maybe identical | Rattus norvegicus |
2.6.1.64 | EC 2.6.1.7 | maybe identical | Rattus norvegicus |
2.6.1.64 | KAT/GTK | - |
Rattus norvegicus |
2.6.1.64 | kynurenine aminotransferase/glutamine transaminase K | - |
Rattus norvegicus |