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Literature summary extracted from
- Enzymatic properties of uroporphyrinogen III cosynthetase (1971), Biochemistry, 10, 4669-4675.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.75 | Coproporphyrins | - |
Mus musculus | |
| 4.2.1.75 | uroporphyrinogen III | product inhibition | Mus musculus |  |
| 4.2.1.75 | Uroporphyrins | - |
Mus musculus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.75 | Mus musculus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.2.1.75 | - |
Mus musculus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.2.1.75 | spleen | - |
Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.75 | Hydroxymethylbilane | - |
Mus musculus | Uroporphyrinogen III | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.75 | 7.7 | 7.9 | - |
Mus musculus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.75 | 6.5 | 8.5 | at pH 6.5: 10% of optimum activity, at pH 8.5: 30% of optimum activity | Mus musculus |
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Release 2023.1 (January 2023)
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