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Literature summary extracted from

  • Gardell, S.J.; Craik, C.S.; Clauser, E.; Goldsmith, E.J.; Stewart, C.B.; Graf, M.; Rutter, W.J.
    A novel rat carboxypeptidase, CPA2: characterization, molecular cloning, and evolutionary implications on substrate specificity in the carboxypeptidase gene family (1988), J. Biol. Chem., 263, 17828-17836.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.17.1
-
 Rattus norvegicus
3.4.17.15
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.17.1 additional information
-
 additional information
-
 Rattus norvegicus
3.4.17.1 0.0346
-
 N-carbobenzoxy-Gly-Gly-L-Phe carboxypeptidase 1 Rattus norvegicus
3.4.17.1 0.0449
-
 N-carbobenzoxy-Gly-L-Phe carboxypeptidase 1 Rattus norvegicus
3.4.17.1 0.143
-
 N-carbobenzoxy-Gly-L-Tyr carboxypeptidase 1 Rattus norvegicus
3.4.17.1 0.145
-
 N-carbobenzoxy-Gly-L-Tyr carboxypeptidase 2 Rattus norvegicus
3.4.17.1 0.314
-
 N-carbobenzoxy-Gly-Gly-L-Phe carboxypeptidase 2 Rattus norvegicus
3.4.17.1 0.74
-
 N-carbobenzoxy-Gly-Gly-L-Leu carboxypeptidase 1 Rattus norvegicus
3.4.17.1 0.985
-
 N-carbobenzoxy-Gly-L-Phe carboxypeptidase 2 Rattus norvegicus
3.4.17.1 6.53
-
 N-carbobenzoxy-Gly-Gly-L-Leu carboxypeptidase 2 Rattus norvegicus
3.4.17.15 0.127
-
 benzyloxycarbonyl-Gly-Trp
-
 Rattus norvegicus
3.4.17.15 0.145
-
 Benzyloxycarbonyl-Gly-Tyr
-
 Rattus norvegicus
3.4.17.15 0.314
-
 benzyloxycarbonyl-Gly-Gly-Phe
-
 Rattus norvegicus
3.4.17.15 6.53
-
 benzyloxycarbonyl-Gly-Gly-Leu
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.1 Rattus norvegicus
-
 carboxypeptidase A 2, evolutionary relationships between rat carboxypeptidases
-
3.4.17.15 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.17.15
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.1 pancreas
-
 Rattus norvegicus
-
3.4.17.15 pancreas
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.1 N-carbobenzoxy-Gly-Gly-L-Leu + H2O
-
 Rattus norvegicus N-carbobenzoxy-Gly-Gly + L-Leu
-
 ir
3.4.17.1 N-carbobenzoxy-Gly-Gly-L-Phe + H2O
-
 Rattus norvegicus N-carbobenzoxy-Gly-Gly + L-Phe
-
 ir
3.4.17.1 N-carbobenzoxy-Gly-L-Phe + H2O
-
 Rattus norvegicus N-carbobenzoxy-Gly + L-Phe
-
 ir
3.4.17.1 N-carbobenzoxy-Gly-L-Tyr + H2O
-
 Rattus norvegicus N-carbobenzoxy-Gly + L-Tyr
-
 ir
3.4.17.15 benzyloxycarbonyl-Gly-Gly-Leu + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.17.15 benzyloxycarbonyl-Gly-Gly-Phe + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.17.15 benzyloxycarbonyl-Gly-Gly-Trp + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.17.15 benzyloxycarbonyl-Gly-Phe + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.17.15 benzyloxycarbonyl-Gly-Trp + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.17.15 benzyloxycarbonyl-Gly-Tyr + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.17.15 additional information carboxy-terminal amino acids with aromatic or branched aliphatic side chains are preferred Rattus norvegicus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.17.1 More amino acid composition described Rattus norvegicus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.17.1 additional information
-
 additional information
-
 Rattus norvegicus
3.4.17.1 14
-
 N-carbobenzoxy-Gly-Gly-L-Leu carboxypeptidase 2 Rattus norvegicus
3.4.17.1 14.4
-
 N-carbobenzoxy-Gly-L-Tyr carboxypeptidase 1 Rattus norvegicus
3.4.17.1 16.8
-
 N-carbobenzoxy-Gly-L-Phe carboxypeptidase 2 Rattus norvegicus
3.4.17.1 22.4
-
 N-carbobenzoxy-Gly-L-Phe carboxypeptidase 1 Rattus norvegicus
3.4.17.1 26.2
-
 N-carbobenzoxy-Gly-L-Tyr carboxypeptidase 2 Rattus norvegicus
3.4.17.1 57
-
 N-carbobenzoxy-Gly-Gly-L-Phe carboxypeptidase 1 Rattus norvegicus
3.4.17.1 97
-
 N-carbobenzoxy-Gly-Gly-L-Phe carboxypeptidase 2 Rattus norvegicus
3.4.17.1 199
-
 N-carbobenzoxy-Gly-Gly-L-Leu carboxypeptidase 1 Rattus norvegicus
3.4.17.15 14
-
 benzyloxycarbonyl-Gly-Gly-Leu
-
 Rattus norvegicus
3.4.17.15 14.4
-
 Benzyloxycarbonyl-Gly-Tyr
-
 Rattus norvegicus
3.4.17.15 16.8
-
 Benzyloxycarbonyl-Gly-Phe
-
 Rattus norvegicus
3.4.17.15 26.6
-
 benzyloxycarbonyl-Gly-Trp
-
 Rattus norvegicus
3.4.17.15 96.9
-
 benzyloxycarbonyl-Gly-Gly-Trp
-
 Rattus norvegicus