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Literature summary extracted from

  • Oberlies, G.; Fuchs, G.; Thauer, R.K.
    Acetate thiokinase and the assimilation of acetate in Methanobacterium thermoautotrophicum (1980), Arch. Microbiol., 128, 248-252.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.2.1.1 P1,P5-di(adenosine-5)pentaphosphate inhibits ADP formation Methanothermobacter thermautotrophicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.2.1.1 0.04
-
 acetate
-
 Methanothermobacter thermautotrophicus
6.2.1.1 0.05
-
 CoA value above 0.05 mM Methanothermobacter thermautotrophicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.2.1.1 additional information Methanothermobacter thermautotrophicus acetate thiokinase is not involved in autotrophic CO2 fixation ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.3 Methanothermobacter thermautotrophicus
-
-
-
6.2.1.1 Methanothermobacter thermautotrophicus
-
 specific activity of the enzyme is high in cells grown with limited H2 and CO2 supply. It is low in exponentially grown cells
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.3 ATP + AMP
-
 Methanothermobacter thermautotrophicus ADP + ADP
-
 ?
6.2.1.1 ATP + acetate + CoA
-
 Methanothermobacter thermautotrophicus AMP + diphosphate + acetyl-CoA
-
 ?
6.2.1.1 additional information acetate thiokinase is not involved in autotrophic CO2 fixation Methanothermobacter thermautotrophicus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
6.2.1.1 8.2
-
-
 Methanothermobacter thermautotrophicus