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Literature summary extracted from

  • Hawkes, T.R.; Thomas, P.G.; Edwards, L.S.; Rayner, S.J.; Wilkinson, K.W.
    Purification and characterization of the imidazoleglycerol-phosphate dehydratase of Saccharomyces cerevisiae from recombinant Escherichia coli (1995), Biochem. J., 306, 385-397.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.19 3-Amino-1,2,4-triazole Ki: 0.12 mM Saccharomyces cerevisiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.1.19 0.1
-
 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate
-
 Saccharomyces cerevisiae

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.2.1.19 Mn2+ essential for assembly of subunits Saccharomyces cerevisiae

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.2.1.19 23833
-
 x * 23833, light scattering Saccharomyces cerevisiae
4.2.1.19 70000
-
 trimeric enzyme in absence of Mn2+, gel filtration Saccharomyces cerevisiae
4.2.1.19 500000
-
 polymeric enzyme in presence of Mn2+, gel filtration Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.19 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.19
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.19 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate
-
 Saccharomyces cerevisiae 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
4.2.1.19 polymer x * 23833, light scattering Saccharomyces cerevisiae