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Literature summary extracted from

  • Moore, J.D.; Lamb, H.K.; Garbe, T.; Servos, S.; Dougan, G.; Charles, I.G.; Hawkins, A.R.
    Inducible overproduction of the Aspergillus nidulans pentafunctional AROM protein and the type-I and -II 3-dehydroquinase from Salmonella typhi and Mycobacterium tuberculosis (1992), Biochem. J., 287, 173-181.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.1.10
-
 Aspergillus nidulans
4.2.1.10 overexpression in Escherichia coli Mycobacterium tuberculosis
4.2.1.10 overexpression in Escherichia coli Salmonella enterica subsp. enterica serovar Typhi

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.10 Aspergillus nidulans
-
 pentafunctional AROM protein with activities of EC 1.1.1.25, EC 4.2.1.10, 5-dehydroquinate synthetase, 3-enolpyruvylshikimic acid 5-phosphate synthetase and shikimic acid kinase
-
4.2.1.10 Mycobacterium tuberculosis
-
-
-
4.2.1.10 Salmonella enterica subsp. enterica serovar Typhi
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.10
-
 Mycobacterium tuberculosis

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.2.1.10 43.3
-
-
 Mycobacterium tuberculosis
4.2.1.10 1284
-
-
 Aspergillus nidulans

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.10 3-dehydroquinate
-
 Aspergillus nidulans 3-dehydroshikimate + H2O
-
 ?
4.2.1.10 3-dehydroquinate
-
 Salmonella enterica subsp. enterica serovar Typhi 3-dehydroshikimate + H2O
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.2.1.10 20
-
 3-dehydroquinate
-
 Salmonella enterica subsp. enterica serovar Typhi