Literature summary extracted from

Collins, S.P.; Uhler, M.D.
Cyclic AMP- and cyclic GMP-dependent protein kinases differ in their regulation of cyclic AMP response element-dependent gene transcription (1999), J. Biol. Chem., 274, 8391-8404.

Protein Variants

EC Number	Protein Variants	Comment	Organism
2.7.11.12	S79D	replacement of an autophosphorylated Ser79 of cGKIbeta with an aspartic acid results in a mutant kinase with constitutive kinase activity in vitro and in vivo. The cGKIbetaS79D mutant localized to the cytoplasm and is only a weak activator of CRE-dependent gene transcription	Mus musculus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.11.12	Mus musculus	P0C605	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.11.12	ATP + protein	autophosphorylation	Mus musculus	ADP + phosphoprotein	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.11.12	cGMP-dependent protein kinase 1, beta isozyme	-	Mus musculus

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.7.11.12	cGMP	dependent on	Mus musculus

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Release 2023.1 (January 2023)