show Proteolytic cleavage of exotoxin A from Pseudomonas aeruginosa: formation of an ADP-ribosyltransferase active fragment by the action of Pseudomonas elastase
Sanai, Y.; Morihara, K.; Tsuzuki, H.; Homma, J.Y.; Kato, I.; FEBS Lett. 120, 131-134 (1980)
Data extracted from this reference:
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.4.2.36
Elastase
inactivation follows pseudo-first order kinetic
Pseudomonas aeruginosa
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.4.2.36
extracellular
exotoxin A
Pseudomonas aeruginosa
-
-
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.4.2.36
72000
-
1 * 72000, exotoxin A, SDS-PAGE
Pseudomonas aeruginosa
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.4.2.36
NAD+ + elongation factor 2
Pseudomonas aeruginosa
-
nicotinamide + ADPribose-elongation factor 2
-
Pseudomonas aeruginosa
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.4.2.36
Pseudomonas aeruginosa
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
2.4.2.36
exotoxin A
Pseudomonas aeruginosa
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.4.2.36
culture supernatant
-
Pseudomonas aeruginosa
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.2.36
NAD+ + elongation factor 2
-
489799
Pseudomonas aeruginosa
nicotinamide + ADPribose-elongation factor 2
-
489799
Pseudomonas aeruginosa
-
Subunits
EC Number
Subunits
Commentary
Organism
2.4.2.36
monomer
1 * 72000, exotoxin A, SDS-PAGE
Pseudomonas aeruginosa
Temperature Optimum [°C]
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
2.4.2.36
25
-
assay at
Pseudomonas aeruginosa
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.4.2.36
Elastase
inactivation follows pseudo-first order kinetic
Pseudomonas aeruginosa
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.4.2.36
extracellular
exotoxin A
Pseudomonas aeruginosa
-
-
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.4.2.36
72000
-
1 * 72000, exotoxin A, SDS-PAGE
Pseudomonas aeruginosa
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.4.2.36
NAD+ + elongation factor 2
Pseudomonas aeruginosa
-
nicotinamide + ADPribose-elongation factor 2
-
Pseudomonas aeruginosa
-
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
2.4.2.36
exotoxin A
Pseudomonas aeruginosa
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.4.2.36
culture supernatant
-
Pseudomonas aeruginosa
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.2.36
NAD+ + elongation factor 2
-
489799
Pseudomonas aeruginosa
nicotinamide + ADPribose-elongation factor 2
-
489799
Pseudomonas aeruginosa
-
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
2.4.2.36
monomer
1 * 72000, exotoxin A, SDS-PAGE
Pseudomonas aeruginosa
Temperature Optimum [°C] (protein specific)
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
2.4.2.36
25
-
assay at
Pseudomonas aeruginosa