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Literature summary extracted from

  • Sato, T.; Furukawa, K.; Bakker, H.; Van den Eijnden, D.H.; Van Die, I.
    Molecular cloning of a human cDNA encoding beta-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal: GlcNAc beta-1,4-galactosyltransferase (1998), Proc. Natl. Acad. Sci. USA, 95, 472-477.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.38 enzyme fused to protein A is expressed as a soluble form in COS-7 cells Homo sapiens
2.4.1.90 enzyme fused to protein A is expressed as a soluble form in COS-7 cells Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.38 Mn2+ 20 mM, stimulates Homo sapiens
2.4.1.90 Mn2+ 20 mM, stimulates Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.38 Homo sapiens O43286
-
-
2.4.1.90 Homo sapiens O43286
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.38 MRK-nu-1 cell
-
 Homo sapiens
-
2.4.1.90 MRK-nu-1 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.38 UDPgalactose + GlcNAcbeta-S-p-NP
-
 Homo sapiens UDP + Galbeta1-4 GlcNAcbeta-S-p-NP
-
 ?
2.4.1.38 UDPgalactose + GlcNAcbeta1-6(GlcNAcbeta1-2)Manalpha1-3Manbeta1-O(CH2)8COOCH2-mNP
-
 Homo sapiens UDP + Galbeta1-4 GlcNAcbeta1-6(GlcNAcbeta1-2)Manalpha1-3Manbeta1-O(CH2)8COOCH2-mNP
-
 ?
2.4.1.38 UDPgalactose + glucose enzyme has no lactose synthase activity in presence of alpha-lactalbumin Homo sapiens lactose + UDP
-
 ?
2.4.1.38 UDPgalactose + N-acetylglucosamine 7% of the activity with GlcNAcbeta-S-pNP Homo sapiens UDP + N-acetyllactosamine
-
 ?
2.4.1.90 UDPgalactose + GlcNAcbeta-S-p-NP
-
 Homo sapiens UDP + Galbeta1-4 GlcNAcbeta-S-p-NP
-
 ?
2.4.1.90 UDPgalactose + GlcNAcbeta1-6(GlcNAcbeta1-2)Manalpha1-3Manbeta1-O(CH2)8COOCH2-mNP
-
 Homo sapiens UDP + Galbeta1-4 GlcNAcbeta1-6(GlcNAcbeta1-2)Manalpha1-3Manbeta1-O(CH2)8COOCH2-mNP
-
 ?
2.4.1.90 UDPgalactose + glucose enzyme has no lactose synthase activity in presence of alpha-lactalbumin Homo sapiens lactose + UDP
-
 ?
2.4.1.90 UDPgalactose + N-acetylglucosamine 7% of the activity with GlcNAcbeta-S-pNP Homo sapiens UDP + N-acetyllactosamine
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.38 7
-
-
 Homo sapiens
2.4.1.90 7
-
-
 Homo sapiens