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Literature summary extracted from

  • Zimmerman, J.W.; Robbins, P.W.
    The hydrophobic domain of dolichyl-phosphate-mannose synthase is not essential for enzyme activity or growth in Saccharomyces cerevisiae (1993), J. Biol. Chem., 268, 16746-16753.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
2.4.1.83 additional information mutant enzymes containing successive deletions or mutations of the hydrophobic region exhibit decreased transferase activity in vitro compared to the wild type enzyme, but the sequence is not essential for growth or for protein glycosylation. Although deletion of the entire hydrophobic region results in a soluble protein, mutant proteins containing 3 or 8 hydrophobic residues are still membrane-associated Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.83 endoplasmic reticulum membrane Saccharomyces cerevisiae 5783
-
2.4.1.83 membrane of the endoplasmic reticulum Saccharomyces cerevisiae 16020
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.83 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.83 GDPmannose + dolichyl phosphate
-
 Saccharomyces cerevisiae GDP + dolichyl D-mannosyl phosphate
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