EC Number | Cloned (Comment) | Organism |
---|---|---|
2.4.1.47 | CGT gene is cloned, sequenced and characterized, cell-specific and highly time-regulated expression of the gene | Mus musculus |
2.4.1.47 | cloning and characterization of the CGT gene, chromosomal localization as a single-copy gene to 4q26 | Homo sapiens |
2.4.1.47 | cloning of the full-length CGT cDNA, open reading frame of 1623 bp encodes a 541 amino acids core protein | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.4.1.47 | endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
2.4.1.47 | endoplasmic reticulum | translation product with N-terminal 20 amino acids signal sequence, C-terminal 23 amino acids transmembrane domain and KKVK endoplasmic reticulum retention signal | Rattus norvegicus | 5783 | - |
2.4.1.47 | membrane | - |
Homo sapiens | 16020 | - |
2.4.1.47 | membrane | with C-terminal 23 amino acids transmembrane domain | Rattus norvegicus | 16020 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.4.1.47 | 64000 | - |
x * 64000 | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.47 | additional information | Homo sapiens | - |
? | - |
? | |
2.4.1.47 | additional information | Rattus norvegicus | - |
? | - |
? | |
2.4.1.47 | additional information | Mus musculus | key enzyme in the biosynthesis of cerebrosides and sulfatides, cell-specific and highly time-regulated expression of the CGT gene is thought to play an important role in oligodendrocyte and Schwann cell differentiation | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.47 | Homo sapiens | - |
- |
- |
2.4.1.47 | Mus musculus | - |
- |
- |
2.4.1.47 | Rattus norvegicus | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
2.4.1.47 | glycoprotein | - |
Homo sapiens |
2.4.1.47 | glycoprotein | high mannose glycoprotein | Rattus norvegicus |
2.4.1.47 | glycoprotein | translation product with 3 putative N-glycosylation sites | Rattus norvegicus |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.4.1.47 | - |
Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.1.47 | brain | - |
Mus musculus | - |
2.4.1.47 | brain | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.47 | additional information | - |
Homo sapiens | ? | - |
? | |
2.4.1.47 | additional information | - |
Rattus norvegicus | ? | - |
? | |
2.4.1.47 | additional information | key enzyme in the biosynthesis of cerebrosides and sulfatides, cell-specific and highly time-regulated expression of the CGT gene is thought to play an important role in oligodendrocyte and Schwann cell differentiation | Mus musculus | ? | - |
? | |
2.4.1.47 | UDPgalactose + 2-(2-hydroxyacyl)sphingosine | - |
Mus musculus | 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine + UDP | - |
? | |
2.4.1.47 | UDPgalactose + 2-(2-hydroxyacyl)sphingosine | - |
Homo sapiens | 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine + UDP | - |
? | |
2.4.1.47 | UDPgalactose + 2-(2-hydroxyacyl)sphingosine | - |
Rattus norvegicus | 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine + UDP | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.4.1.47 | ? | x * 64000 | Rattus norvegicus |