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Literature summary extracted from

  • Hirota, M.; Egami, H.; Ogawa, M.
    Augmentation of UDP-GalNAc:Fuca1-2Gal-a1-3-N-acetylgalactosaminyl transferase activity in nitrosamine-induced hamster pancreatic cancers (2000), J. Exp. Clin. Cancer Res., 19, 235-239.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.40 0.048
-
 UDP-GalNAc pancreatic cancer cell line, distal colon Mesocricetus auratus
2.4.1.40 0.39
-
 2'-fucosyllactose distal colon Mesocricetus auratus
2.4.1.40 0.47
-
 2'-fucosyllactose pancreatic cancer cell line Mesocricetus auratus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.40 membrane
-
 Mesocricetus auratus 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.40 Mn2+
-
 Mesocricetus auratus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.40 Mesocricetus auratus
-
 Syrian hamster
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.40 colon middle and distal Mesocricetus auratus
-
2.4.1.40 pancreas produces blood group-A antigen only in pancreatic cancer cells, induced by N-nitrosobis(2-oxopropyl)amine Mesocricetus auratus
-
2.4.1.40 stomach antrum Mesocricetus auratus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.40 UDP-N-acetyl-D-galactosamine + 2'-fucosyllactose
-
 Mesocricetus auratus UDP + N-acetyl-alpha-D-galactosaminyl-2'-fucosyllactose
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.40 7
-
 pancreatic cancer cell line, antrum and distal colon Mesocricetus auratus