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Literature summary extracted from

  • Yu, L.C.; Lee, H.L.; Chan, Y.S.; Lin, M.
    The molecular basis for the B(A) allele: an amino acid alteration in the human histoblood group B alpha-(1,3)-galactosyltransferase increases its intrinsic alpha-(1,3)-N-acetylgalactosaminyltransferase activity (1999), Biochem. Biophys. Res. Commun., 262, 487-493.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.37 Mn2+
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.37 Homo sapiens
-
 only four amino acids are responsible for B and A blood group enzymes R176G, G235S, L266M and G268A, the latter two amino acids are responsible for the difference in donor specificity and the first two have roles in acceptor binding and turnover
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2.4.1.37 Homo sapiens
-
 genotype Wu4, P234A-mutant, heterozygot B/0
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.37 UDP-galactose + 2'-fucosyllactose
-
 Homo sapiens UDP + alpha-D-galactosyl-1,3-[2'-fucosyllactose]
-
 ?
2.4.1.37 UDP-galactose + L-fucosyl-alpha-1,2-beta-D-galactosyl-O(CH2)7CH3
-
 Homo sapiens UDP + alpha-D-galactosyl-1,3-[alpha-L-fucosyl-1,2]-beta-D-galactosyl-O(CH2)7CH3
-
 ?
2.4.1.37 UDP-N-acetylgalactosamine + 2'-fucosyllactose
-
 Homo sapiens UDP + N-acetyl-alpha-D-galactosyl-1,3-[2'-fucosyllactose]
-
 ?