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Literature summary extracted from

  • Paquet, M.R.; Moscarello, M.A.
    A kinetic comparison of partially purified rat liver Golgi and rat serum galactosyltransferases (1984), Biochem. J., 218, 745-751.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.38 alpha-lactalbumin inhibits reaction with UDPgalactose and N-acetylglucosamine Bos taurus
2.4.1.38 alpha-lactalbumin inhibits reaction with UDPgalactose and N-acetylglucosamine Rattus norvegicus
2.4.1.90 alpha-lactalbumin inhibits reaction with UDPgalactose and N-acetylglucosamine Bos taurus
2.4.1.90 alpha-lactalbumin inhibits reaction with UDPgalactose and N-acetylglucosamine Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.22 0.009
-
 UDPgalactose serum Rattus norvegicus
2.4.1.22 0.023
-
 UDPgalactose liver, Golgi apparatus Rattus norvegicus
2.4.1.22 0.06
-
 UDPgalactose milk Bos taurus
2.4.1.22 1.8
-
 glucose serum Rattus norvegicus
2.4.1.22 2
-
 glucose milk Bos taurus
2.4.1.22 2.3
-
 glucose liver, Golgi apparatus Rattus norvegicus
2.4.1.38 0.043
-
 UDPgalactose
-
 Bos taurus
2.4.1.38 0.052
-
 UDPgalactose enzyme from serum Rattus norvegicus
2.4.1.38 0.065
-
 UDPgalactose enzyme from liver Rattus norvegicus
2.4.1.38 0.33
-
 N-acetylglucosamine enzyme from liver Rattus norvegicus
2.4.1.38 0.5
-
 N-acetylglucosamine
-
 Bos taurus
2.4.1.38 1.49
-
 N-acetylglucosamine
-
 Rattus norvegicus
2.4.1.90 0.043
-
 UDPgalactose
-
 Bos taurus
2.4.1.90 0.052
-
 UDPgalactose enzyme from serum Rattus norvegicus
2.4.1.90 0.065
-
 UDPgalactose enzyme from liver Rattus norvegicus
2.4.1.90 0.33
-
 N-acetylglucosamine enzyme from liver Rattus norvegicus
2.4.1.90 0.5
-
 N-acetylglucosamine
-
 Bos taurus
2.4.1.90 1.49
-
 N-acetylglucosamine
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.22 membrane
-
 Rattus norvegicus 16020
-
2.4.1.22 membrane
-
 Bos taurus 16020
-
2.4.1.22 soluble
-
 Rattus norvegicus
-
-
2.4.1.22 soluble
-
 Bos taurus
-
-
2.4.1.38 Golgi apparatus
-
 Rattus norvegicus 5794
-
2.4.1.38 Golgi apparatus
-
 Bos taurus 5794
-
2.4.1.90 Golgi apparatus
-
 Rattus norvegicus 5794
-
2.4.1.90 Golgi apparatus
-
 Bos taurus 5794
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.38 Mn2+
-
 Bos taurus
2.4.1.38 Mn2+ maximal activity at 3-5 mM Rattus norvegicus
2.4.1.38 Mn2+ optimal concentration 3-5 mM Rattus norvegicus
2.4.1.90 Mn2+
-
 Bos taurus
2.4.1.90 Mn2+ maximal activity at 3-5 mM Rattus norvegicus
2.4.1.90 Mn2+ optimal concentration 3-5 mM Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.22 Bos taurus
-
-
-
2.4.1.22 Rattus norvegicus
-
-
-
2.4.1.38 Bos taurus
-
-
-
2.4.1.38 Rattus norvegicus
-
-
-
2.4.1.90 Bos taurus
-
-
-
2.4.1.90 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.22 partial Rattus norvegicus
2.4.1.38 partial Rattus norvegicus
2.4.1.90 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.22 blood serum
-
 Rattus norvegicus
-
2.4.1.22 liver
-
 Rattus norvegicus
-
2.4.1.22 milk
-
 Rattus norvegicus
-
2.4.1.22 milk
-
 Bos taurus
-
2.4.1.38 liver
-
 Rattus norvegicus
-
2.4.1.38 liver
-
 Bos taurus
-
2.4.1.38 serum
-
 Rattus norvegicus
-
2.4.1.90 liver
-
 Rattus norvegicus
-
2.4.1.90 liver
-
 Bos taurus
-
2.4.1.90 serum
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.22 additional information
-
-
 Rattus norvegicus

Storage Stability

EC Number Storage Stability Organism
2.4.1.38 4°C, purified and concentrated enzyme is stable for 4 weeks Rattus norvegicus
2.4.1.90 4°C, purified and concentrated enzyme is stable for 4 weeks Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.22 UDPgalactose + D-glucose
-
 Rattus norvegicus lactose + UDP
-
 ?
2.4.1.22 UDPgalactose + D-glucose
-
 Bos taurus lactose + UDP
-
 ?
2.4.1.38 UDPgalactose + N-acetylglucosamine
-
 Rattus norvegicus UDP + N-acetyllactosamine
-
 ?
2.4.1.38 UDPgalactose + N-acetylglucosamine
-
 Bos taurus UDP + N-acetyllactosamine
-
 ?
2.4.1.90 UDPgalactose + N-acetylglucosamine
-
 Rattus norvegicus UDP + N-acetyllactosamine
-
 ?
2.4.1.90 UDPgalactose + N-acetylglucosamine
-
 Bos taurus UDP + N-acetyllactosamine
-
 ?