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Literature summary extracted from

  • Styczynski, P.; Green, M.; Puig, J.; Coffman, B.; Tephly, T.
    Purification and properties of a rat liver phenobarbital-inducible 4-hydroxybiphenyl UDP-glucuronosyltransferase (1991), Mol. Pharmacol., 40, 80-84.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.17 0.26
-
 4-Hydroxybiphenyl
-
 Rattus norvegicus
2.4.1.17 1
-
 UDPglucuronate
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.17 microsome
-
 Rattus norvegicus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.17 52500
-
 x * 52500 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.17 Rattus norvegicus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.4.1.17 glycoprotein N-glycosylated Rattus norvegicus

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.17
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.17 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.17 4-hydroxybiphenyl + UDP-glucuronate
-
 Rattus norvegicus UDP + 4-hydroxybiphenyl 4-O-beta-D-glucuronide
-
 ?
2.4.1.17 4-hydroxybiphenyl + UDPglucuronate
-
 Rattus norvegicus UDP + 4-hydroxybiphenyl 4-O-beta-D-glucuronide
-
 ?
2.4.1.17 4-methylumbelliferone + UDP-glucuronate
-
 Rattus norvegicus UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide
-
 ?
2.4.1.17 4-nitrophenol + UDP-glucuronate
-
 Rattus norvegicus 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
2.4.1.17 additional information no activity with androsterone Rattus norvegicus ?
-
 ?
2.4.1.17 additional information no activity with 4-hydroxycoumarin or 7-methoxycoumarin, conjugation of androsterone Rattus norvegicus ?
-
 ?
2.4.1.17 testosterone + UDPglucuronate no activity Rattus norvegicus UDP + testosterone O-glucuronide
-
 ?
2.4.1.17 UDP-alpha-D-glucuronate + chloramphenicol no activity Rattus norvegicus UDP + chloramphenicol beta-D-glucuronide
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.1.17 ? x * 52500 Rattus norvegicus
2.4.1.17 ? all values determined by SDS-PAGE Rattus norvegicus