Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Illing, H.P.A.; Dutton, G.J.
    Some properties of the uridine diphosphate glucuronyltransferase activity synthesizing thio-beta-D-glucuronides (1973), Biochem. J., 131, 139-147.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.17 Phenobarbital
-
 Rattus norvegicus
2.4.1.17 Phenobarbital stimulation of the enzyme in cultured 11-day embryo liver Gallus gallus
2.4.1.17 UDP-N-acetylglucosamine activation Gallus gallus
2.4.1.17 UDP-N-acetylglucosamine activation Mus musculus
2.4.1.17 UDP-N-acetylglucosamine activation Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.17 additional information
-
 additional information
-
 Rattus norvegicus
2.4.1.17 additional information
-
 additional information effect of UDP-N-acetylglucosamine as activator Gallus gallus
2.4.1.17 additional information
-
 additional information effect of UDP-N-acetylglucosamine as activator Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.17 microsome
-
 Gallus gallus
-
-
2.4.1.17 microsome
-
 Mus musculus
-
-
2.4.1.17 microsome
-
 Rattus norvegicus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.17 Mg2+ no effect Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.17 Gallus gallus
-
-
-
2.4.1.17 Mus musculus
-
-
-
2.4.1.17 Rattus norvegicus
-
 Wistar strain
-
2.4.1.17 Rattus norvegicus
-
 Gunn strain
-
2.4.1.17 Rattus norvegicus
-
 distribution in Wistar and Gunn strain
-
2.4.1.17 Rattus norvegicus Gunn
-
 Gunn strain
-
2.4.1.17 Rattus norvegicus Gunn
-
 distribution in Wistar and Gunn strain
-
2.4.1.17 Rattus norvegicus Wistar
-
 Wistar strain
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.17 kidney
-
 Gallus gallus
-
2.4.1.17 kidney
-
 Mus musculus
-
2.4.1.17 kidney
-
 Rattus norvegicus
-
2.4.1.17 liver
-
 Gallus gallus
-
2.4.1.17 liver
-
 Mus musculus
-
2.4.1.17 liver
-
 Rattus norvegicus
-
2.4.1.17 stomach
-
 Mus musculus
-

Storage Stability

EC Number Storage Stability Organism
2.4.1.17 4°C, microsomal preparation: increase of activity towards 4-nitrophenol, maximum of activation at 3 days storage Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.17 4-nitrothiophenol + UDP-glucuronate
-
 Gallus gallus 4-nitrothiophenyl thio-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 4-nitrothiophenol + UDP-glucuronate
-
 Mus musculus 4-nitrothiophenyl thio-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 4-nitrothiophenol + UDP-glucuronate
-
 Rattus norvegicus 4-nitrothiophenyl thio-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 4-nitrothiophenol + UDP-glucuronate
-
 Rattus norvegicus Gunn 4-nitrothiophenyl thio-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 4-nitrothiophenol + UDP-glucuronate
-
 Rattus norvegicus Wistar 4-nitrothiophenyl thio-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 thiophenol + UDPglucuronate
-
 Rattus norvegicus thiophenyl thio-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 thiophenol + UDPglucuronate
-
 Rattus norvegicus Gunn thiophenyl thio-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 thiophenol + UDPglucuronate
-
 Rattus norvegicus Wistar thiophenyl thio-beta-D-glucuronide + UDP
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.17 7.3 7.8 4-thionitrophenol, thiophenol and 4-nitrophenol as substrates Rattus norvegicus
2.4.1.17 7.4
-
 4-nitrothiophenol Rattus norvegicus