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Literature summary extracted from

  • Mackenzie, P.I.; Hjelmeland, L.M.; Owens, I.S.
    Purification and immunochemical characterization of a low-pI form of UDP glucuronosyltransferase from mouse liver (1984), Arch. Biochem. Biophys., 231, 487-497.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.17 Phospholipids no effect on glucuronidation of 1-naphthol, 4-nitrophenol, testosterone, 4-methylumbelliferone, morphine Mus musculus
2.4.1.17 Phospholipids 2fold activation of glucuronidation of 3-hydroxybenzo[a]pyrene, between 3fold and 4fold activation of glucuronidation of phenolphthalein Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.17 additional information immunochemical experiments Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.17 microsome
-
 Mus musculus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.17 51000
-
 x * 51000 Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.17 Mus musculus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.4.1.17 phospholipoprotein less than 1 mol phospholipid per mol of enzyme Mus musculus

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.17
-
 Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.17 liver
-
 Mus musculus
-

Storage Stability

EC Number Storage Stability Organism
2.4.1.17 4°C, at least 6 days Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.17 1-naphthol + UDP-glucuronate
-
 Mus musculus naphth-1-yl-beta-D-glucuronide + UDP
-
 ?
2.4.1.17 3-hydroxybenzo[a]pyrene + UDPglucuronate
-
 Mus musculus UDP + 3-hydroxybenzo[a]pyrene-O-glucuronide
-
 ?
2.4.1.17 4-methylumbelliferone + UDP-glucuronate
-
 Mus musculus UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide
-
 ?
2.4.1.17 4-nitrophenol + UDP-glucuronate
-
 Mus musculus 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
2.4.1.17 morphine + UDP-glucuronate
-
 Mus musculus UDP + morphine 3,6-diglucuronide
-
 ?
2.4.1.17 phenolphthalein + UDPglucuronate
-
 Mus musculus UDP + phenolphthalein O-glucuronide
-
 ?
2.4.1.17 testosterone + UDPglucuronate
-
 Mus musculus UDP + testosterone O-glucuronide
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.1.17 ? all values determined by SDS-PAGE Mus musculus
2.4.1.17 ? x * 51000 Mus musculus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.4.1.17 24
-
 1 d, more than 50% loss of activity Mus musculus