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Literature summary extracted from
- Purification and characterization of cell-associated glucosyltransferase synthesizing insoluble glucan from Streptococcus mutans serotype c (1989), J. Gen. Microbiol., 135, 2055-2063.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.4.1.140 | Dextran T10 | 1.7fold stimulation | Streptococcus mutans |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.4.1.140 | additional information | below a sodium phosphate buffer concentration of 50 mM the activity is reduced by 75% | Streptococcus mutans |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 2.4.1.140 | 16.3 | - |
sucrose | - |
Streptococcus mutans |  |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 2.4.1.140 | cell associated | - |
Streptococcus mutans | - |
- |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 2.4.1.140 | 158000 | - |
x * 158000, SDS-PAGE with and without 2-mercaptoethanol | Streptococcus mutans |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.4.1.140 | Streptococcus mutans | - |
Ingbritt, serotype c | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 2.4.1.140 | - |
Streptococcus mutans |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 2.4.1.140 | 7.31 | - |
- |
Streptococcus mutans |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.4.1.140 | sucrose + alpha-D-glucan | - |
Streptococcus mutans | alternating-1,6-1,3-alpha-D-glucan | the product is an insoluble D-glucan that consists of 76 mol% 1,3-alpha-linked glucose and 24 mol% 1,6-alpha-linked glucose | ? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 2.4.1.140 | ? | x * 158000, SDS-PAGE with and without 2-mercaptoethanol | Streptococcus mutans |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 2.4.1.140 | 6.5 | - |
- |
Streptococcus mutans |
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Release 2023.1 (January 2023)
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