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Literature summary extracted from

  • Matern, H.; Matern, S.
    Control of dolichyl phosphoglucose formation in human liver microsomes. Kinetic and inhibition studies of nucleosides, nucleotides and analogues of UDPglucose (1989), Biochim. Biophys. Acta, 1004, 67-72.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.117 UDP
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.117 0.00015
-
 UDP-glucose pH 7.2 Homo sapiens
2.4.1.117 0.00033
-
 UDP-glucose pH 5.3 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.117 microsome
-
 Homo sapiens
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.117 Ca2+ divalent cation required, maximum stimulation in presence of Ca2+. Co2+, Mg2+ or Mn2+ can replace Ca2+ Homo sapiens
2.4.1.117 Co2+ divalent cation required, maximum stimulation in presence of Ca2+. Co2+, Mg2+ or Mn2+ can replace Ca2+ Homo sapiens
2.4.1.117 Mg2+ divalent cation required, maximum stimulation in presence of Ca2+. Co2+, Mg2+ or Mn2+ can replace Ca2+ Homo sapiens
2.4.1.117 Mn2+ divalent cation required, maximum stimulation in presence of Ca2+. Co2+, Mg2+ or Mn2+ can replace Ca2+ Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.117 Homo sapiens
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
2.4.1.117 UDP-alpha-D-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate sequential mechanism Homo sapiens
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.117 liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.117 UDP-glucose + dolichyl phosphate
-
 Homo sapiens UDP + dolichyl beta-D-glucosyl phosphate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.117 5.3
-
 second optimum at pH 7.2 Homo sapiens
2.4.1.117 7.2
-
 second optimum at pH 5.3 Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.1.117 0.1
-
 UDP at pH 7.2 Homo sapiens
2.4.1.117 0.17
-
 UDP at pH 5.3 Homo sapiens