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Literature summary extracted from
- Comparative catalytic properties of liver glycogen synthases from adult and newborn rats (1980), J. Biol. Chem., 255, 1351-1357.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.4.1.11 | glucose 6-phosphate | - |
Rattus norvegicus |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.4.1.11 | ATP | - |
Rattus norvegicus | |
| 2.4.1.11 | phosphate | UDP-glucose reverses inhibition of newborn enzyme | Rattus norvegicus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 2.4.1.11 | additional information | - |
additional information | dependence on glucose 6-phosphate concentration | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.4.1.11 | UDP-glucose + glycogen | Rattus norvegicus | glycogen production | glycogen + UDP | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.4.1.11 | Rattus norvegicus | - |
Sprague Dawley, rat | - |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 2.4.1.11 | phosphoprotein | - |
Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 2.4.1.11 | liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 2.4.1.11 | 4.96 | - |
- |
Rattus norvegicus |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 2.4.1.11 | -80°C, with 5 mM glucose-6-phosphate, stable for at least 4 to 6 months | Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.4.1.11 | UDP-glucose + glycogen | - |
Rattus norvegicus | glycogen + UDP | - |
? | |
| 2.4.1.11 | UDP-glucose + glycogen | glycogen production | Rattus norvegicus | glycogen + UDP | - |
? | |
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Release 2023.1 (January 2023)
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