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Literature summary extracted from

  • Nuttall, F.Q.; Gannon, M.C.
    Allosteric regulation of glycogen synthase in liver. A physiological dilemma (1993), J. Biol. Chem., 268, 13286-13290.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.11 ADP
-
 Rattus norvegicus
2.4.1.11 ATP almost complete inhibition at 5 mM Rattus norvegicus
2.4.1.11 phosphate 0.8-2 mM Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.11 UDP-glucose + glycogen Rattus norvegicus
-
 glycogen + UDP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.11 Rattus norvegicus
-
 Sprague Dawley, rat
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.11 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.11 UDP-glucose + glycogen
-
 Rattus norvegicus glycogen + UDP
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.11 7
-
 synthase I, broad pH optimum Rattus norvegicus
2.4.1.11 8.5
-
 synthase I, narrow pH optimum Rattus norvegicus