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Literature summary extracted from

  • Paige, L.A.; Zheng, G.Q.; DeFrees, S.A.; Cassady, J.M.; Geahlen, R.L.
    Metabolic activation of 2-substituted derivatives of myristic acid to form potent inhibitors of myristoyl CoA:protein N-myristoyltransferase (1990), Biochemistry, 29, 10566-10573.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.97 1-Bromo-2-fluorotetradecane
-
 Mus musculus
2.3.1.97 1-O-Acetyl-2-fluorotetradecane
-
 Mus musculus
2.3.1.97 2-Bromomyristic acid
-
 Mus musculus
2.3.1.97 2-bromomyristoyl-CoA
-
 Mus musculus
2.3.1.97 2-Fluoromyristic acid
-
 Mus musculus
2.3.1.97 2-fluoromyristoyl-CoA
-
 Mus musculus
2.3.1.97 2-Fluorotetradecan-1-ol
-
 Mus musculus
2.3.1.97 2-Hydroxymyristic acid
-
 Mus musculus
2.3.1.97 2-hydroxymyristoyl-CoA
-
 Mus musculus
2.3.1.97 S-(2-Oxo)-pentadecyl-CoA strong Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.97 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.97 brain
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.97 myristoyl-CoA + glycylpeptide
-
 Mus musculus N-myristoylglycylpeptide + CoA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.97 NMT
-
 Mus musculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.97 7.8
-
 assay at Mus musculus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.1.97 0.045
-
 2-hydroxymyristoyl-CoA
-
 Mus musculus
2.3.1.97 0.1
-
 2-Bromomyristic acid
-
 Mus musculus
2.3.1.97 0.2
-
 2-Hydroxymyristic acid
-
 Mus musculus
2.3.1.97 0.2
-
 2-fluoromyristoyl-CoA
-
 Mus musculus
2.3.1.97 0.45
-
 2-bromomyristoyl-CoA
-
 Mus musculus