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Literature summary extracted from

  • Baker, R.R.; Chang, H.Y.
    Alkylglycerophosphate acetyltransferase and lyso platelet activating factor acetyltransferase, two key enzymes in the synthesis of platelet activating factor, are found in neuronal nuclei isolated from cerebral cortex (1996), Biochim. Biophys. Acta, 1302, 257-263.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.67 MgATP2- 32% and 54% inhibition at 0.125 and 1 mM respectively in neuronal nuclear fraction Oryctolagus cuniculus
2.3.1.67 oleoyl-CoA 16% and 36% inhibition at 0.002 and 0.01 mM respectively in neuronal nuclear fraction Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.67 0.146
-
 acetyl-CoA microsomal fraction Oryctolagus cuniculus
2.3.1.67 0.214
-
 acetyl-CoA neuronal nuclear fraction Oryctolagus cuniculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.67 microsome
-
 Oryctolagus cuniculus
-
-
2.3.1.67 nucleus neuronal nuclear fraction Oryctolagus cuniculus 5634
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.67 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.67 cerebral cortex
-
 Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.67 additional information
-
-
 Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.67 acetyl-CoA + alkyl-sn-glycero-3-phosphocholine
-
 Oryctolagus cuniculus CoA + 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.67 8.4
-
 assay at Oryctolagus cuniculus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.3.1.67 6 9 neuronal nuclear fraction and microsomal fraction Oryctolagus cuniculus