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Literature summary extracted from

  • Butor, C.; Diaz, S.; Varki, A.
    High level O-acetylation of sialic acids on N-linked oligosaccharides of rat liver membranes. Differential subcellular distribution of 7- and 9-O-acetyl groups and of enzymes involved in their regulation (1993), J. Biol. Chem., 268, 10197-10206.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.3.1.45 enzyme is labile and difficult to solubilize Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.45 Golgi vesicle 7-O- and 9-O-acetylation Rattus norvegicus
-
-
2.3.1.45 lysosomal membrane 7-O-acetylation Rattus norvegicus 5765
-
2.3.1.45 membrane
-
 Rattus norvegicus 16020
-
2.3.1.45 plasma membrane 9-O-acetylation Rattus norvegicus 5886
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.45 acetyl-CoA + sialic acid Rattus norvegicus
-
 CoA + N-acetyl-7-O(or 9-O-)-acetylneuraminate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.45 Rattus norvegicus
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
2.3.1.45 acetyl-CoA + N-acetylneuraminate = CoA + N-acetyl-7-O(or 9-O)-acetylneuraminate 7-O-acetyl groups can migrate to the 9-position Rattus norvegicus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.45 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.45 acetyl-CoA + N-acetylneuraminate glycosidically bound N-acetylneuraminate, alpha2-6 linked Rattus norvegicus CoA + N-acetyl-7-O(or 9-O-)-acetylneuraminate
-
 ?
2.3.1.45 acetyl-CoA + sialic acid
-
 Rattus norvegicus CoA + N-acetyl-7-O(or 9-O-)-acetylneuraminate
-
 ?