BRENDA - Enzyme Database show

Yeast 5-aminolevulinate synthase provides additional chlorophyll precursor in transgenic tobacco

Zavgorodnyaya, A.; Papenbrock, J.; Grimm, B.; Plant J. 12, 169-178 (1997)

Data extracted from this reference:

Application
EC Number
Application
Commentary
Organism
2.3.1.37
nutrition
enzyme expressed in transgenic Nicotiana tabacum plants demonstrate functional complementation in the chlorophyll biosynthesis and open strategies for producing tolerance against inhibitors of the C5 pathway
Saccharomyces cerevisiae
Cloned(Commentary)
EC Number
Commentary
Organism
2.3.1.37
fusion protein of enzyme and plastid-targeting small subunit of ribulose bisphosphate carboxylase for construction of transgenic plants
Saccharomyces cerevisiae
Engineering
EC Number
Amino acid exchange
Commentary
Organism
2.3.1.37
additional information
construction of transgenic plants of Nicotiana tabacum wild-type and mutant deficient in chlorophyll biosynthesis expressing the enzyme targeted to the plastids, functional complementation of the mutant, regulation
Saccharomyces cerevisiae
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.3.1.37
succinyl-CoA + glycine
Saccharomyces cerevisiae
key enzyme in tetrapyrrole biosynthesis
5-aminolevulinate + CoA + CO2
-
Saccharomyces cerevisiae
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.3.1.37
Saccharomyces cerevisiae
-
-
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
2.3.1.37
additional information
-
enzyme expressed in transgenic tabacco plants
Saccharomyces cerevisiae
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.3.1.37
succinyl-CoA + glycine
-
486854
Saccharomyces cerevisiae
5-aminolevulinate + CoA + CO2
-
486854
Saccharomyces cerevisiae
?
2.3.1.37
succinyl-CoA + glycine
key enzyme in tetrapyrrole biosynthesis
486854
Saccharomyces cerevisiae
5-aminolevulinate + CoA + CO2
-
486854
Saccharomyces cerevisiae
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
2.3.1.37
pyridoxal 5'-phosphate
required
Saccharomyces cerevisiae
Application (protein specific)
EC Number
Application
Commentary
Organism
2.3.1.37
nutrition
enzyme expressed in transgenic Nicotiana tabacum plants demonstrate functional complementation in the chlorophyll biosynthesis and open strategies for producing tolerance against inhibitors of the C5 pathway
Saccharomyces cerevisiae
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
2.3.1.37
fusion protein of enzyme and plastid-targeting small subunit of ribulose bisphosphate carboxylase for construction of transgenic plants
Saccharomyces cerevisiae
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
2.3.1.37
pyridoxal 5'-phosphate
required
Saccharomyces cerevisiae
Engineering (protein specific)
EC Number
Amino acid exchange
Commentary
Organism
2.3.1.37
additional information
construction of transgenic plants of Nicotiana tabacum wild-type and mutant deficient in chlorophyll biosynthesis expressing the enzyme targeted to the plastids, functional complementation of the mutant, regulation
Saccharomyces cerevisiae
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.3.1.37
succinyl-CoA + glycine
Saccharomyces cerevisiae
key enzyme in tetrapyrrole biosynthesis
5-aminolevulinate + CoA + CO2
-
Saccharomyces cerevisiae
?
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
2.3.1.37
additional information
-
enzyme expressed in transgenic tabacco plants
Saccharomyces cerevisiae
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.3.1.37
succinyl-CoA + glycine
-
486854
Saccharomyces cerevisiae
5-aminolevulinate + CoA + CO2
-
486854
Saccharomyces cerevisiae
?
2.3.1.37
succinyl-CoA + glycine
key enzyme in tetrapyrrole biosynthesis
486854
Saccharomyces cerevisiae
5-aminolevulinate + CoA + CO2
-
486854
Saccharomyces cerevisiae
?