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Literature summary extracted from

  • Vajda, K.; Ferguson, M.W.J.; Shand, J.H.; Noble, R.C.; Speake, B.K.
    Activities of acyl-CoA:cholesterol acyltransferase and cholesteryl ester hydrolase in the yolk sac membrane of the alligator (Alligator mississippiensis) embryo (1999), Comp. Biochem. Physiol. B, 122, 301-307.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.26 cholesterol day 40 samples, exogenous, added as phosphatidylcholine liposomes, concentration-dependent increase in activity Alligator mississippiensis
2.3.1.26 cholesterol day 50 and 60 samples: not stimulatory Alligator mississippiensis

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.26 Triton WR1339 90% inhibition at 0.3% wt./vol. Alligator mississippiensis

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.26 Alligator mississippiensis
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.26 yolk sac embryo, membrane, at various stages of development Alligator mississippiensis
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.26 additional information
-
 overview: enzyme activity at various days of development with and without exogenous cholesterol Alligator mississippiensis
2.3.1.26 0.000368
-
 day 30 of development, endogenous cholesterol as substrate Alligator mississippiensis
2.3.1.26 0.000808
-
 microsomal preparation from day 40 of development measured at 33°C Alligator mississippiensis
2.3.1.26 0.000824
-
 microsomal preparation from day 40 of development measured at 37°C Alligator mississippiensis
2.3.1.26 0.001585
-
 day 50 of development, endogenous cholesterol as substrate Alligator mississippiensis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.26 oleoyl-CoA + cholesterol
-
 Alligator mississippiensis CoA + cholesteryl oleate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.26 33
-
 assay at, the reaction rate is not significantly different from that at 37°C Alligator mississippiensis
2.3.1.26 37
-
 assay at Alligator mississippiensis