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Literature summary extracted from

  • Truckenmiller, M.E.; Namboodiri, M.A.A.; Brownstein, M.J.; Neale, J.H.
    N-Acetylation of L-aspartate in the nervous system: differential distribution of a specific enzyme (1985), J. Neurochem., 45, 1658-1662.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.17 membrane
-
 Rattus norvegicus 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.17 acetyl-CoA + L-aspartate Rattus norvegicus
-
 CoA + N-acetyl-L-aspartic acid
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.17 Rattus norvegicus
-
 male Sprague-Dawley rat
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.17 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.17 brain
-
 Rattus norvegicus
-
2.3.1.17 additional information highest activity in the brainstem and the spinal cord, lowest activity in the retina, no activity in heart, kidney or liver of rat Rattus norvegicus
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2.3.1.17 spinal cord
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.17 0.0000063
-
 brain Rattus norvegicus
2.3.1.17 0.000011
-
 spinal cord Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.17 acetyl-CoA + L-aspartate
-
 Rattus norvegicus CoA + N-acetyl-L-aspartic acid
-
 ?
2.3.1.17 acetyl-CoA + L-glutamate only 10% activity compared to L-aspartate Rattus norvegicus CoA + N-acetyl-L-glutamic acid
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.17 37
-
 assay at Rattus norvegicus