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Literature summary extracted from

  • Menhard, B.; Zenk, M.H.
    Purification and characterization of acetyl coenzyme A: 10-hydroxytaxane O-acetyltransferase from cell suspension cultures of Taxus chinensis (1999), Phytochemistry, 50, 763-774.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.3.1.163 pharmacology use in synthesis of taxol for anticnacer treatment Taxus cuspidata

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.163 0.061
-
 acetyl-CoA
-
 Taxus cuspidata

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.163 70900
-
 1 * 70900, SDS-PAGE Taxus cuspidata
2.3.1.163 71000
-
 gel filtration Taxus cuspidata

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.163 acetyl-CoA + 10-desacetyltaxuyunnanin C Taxus cuspidata
-
 CoA + taxuyunnanin C
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.163 Taxus cuspidata
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.163
-
 Taxus cuspidata

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.163 2,5,10,14-desacetyltaxuyunnanin C
-
 Taxus cuspidata CoA + 2,5,10-desacetyltaxuyunnanin C
-
 ?
2.3.1.163 acetyl-CoA + 10-desacetyltaxuyunnanin C
-
 Taxus cuspidata CoA + taxuyunnanin C
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.163 monomer 1 * 70900, SDS-PAGE Taxus cuspidata