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Literature summary extracted from

  • Okuyama, H.; Wakil, S.J.
    Positional specificities of acyl coenzyme A: glycerophosphate and acyl coenzyme A: monoacylglycerophosphate acyltransferases in Escherichia coli (1973), J. Biol. Chem., 248, 5197-5205.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.3.1.51 slow freezing inactivates Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.51 MgCl2 at high concentrations Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.15 plasma membrane
-
 Escherichia coli 5886
-
2.3.1.51 membrane
-
 Escherichia coli 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.1.51 additional information no Mg2+-requirement Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.15 Escherichia coli
-
 B
-
2.3.1.15 Escherichia coli B / ATCC 11303
-
 B
-
2.3.1.51 Escherichia coli
-
 B
-
2.3.1.51 Escherichia coli B / ATCC 11303
-
 B
-

Storage Stability

EC Number Storage Stability Organism
2.3.1.51 -15°C to 4°C, particulate preparation, fast-frozen in liquid N2, unstable Escherichia coli
2.3.1.51 -15°C, less than a day Escherichia coli
2.3.1.51 -80°C, particulate preparation, fast-frozen in liquid N2, 3 months Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.15 acyl-CoA + sn-glycerol 3-phosphate exclusively acylates glycerol 3-phosphate at the C-1-position Escherichia coli CoA + 1-acyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 acyl-CoA + sn-glycerol 3-phosphate exclusively acylates glycerol 3-phosphate at the C-1-position Escherichia coli B / ATCC 11303 CoA + 1-acyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 oleoyl-CoA + sn-glycerol 3-phosphate
-
 Escherichia coli CoA + 1-oleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 oleoyl-CoA + sn-glycerol 3-phosphate
-
 Escherichia coli B / ATCC 11303 CoA + 1-oleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 palmitoyl-CoA + sn-glycerol 3-phosphate
-
 Escherichia coli CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 palmitoyl-CoA + sn-glycerol 3-phosphate
-
 Escherichia coli B / ATCC 11303 CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
-
 Escherichia coli CoA + 1,2-diacyl-sn-glycerol 3-phosphate i.e. phosphatidic acid ?
2.3.1.51 acyl-CoA + 2-acyl-sn-glycerol 3-phosphate the enzyme does not acylate 2-acyl-sn-glycerol 3-phosphate Escherichia coli CoA + ?
-
 ?
2.3.1.51 additional information effect of acyl-CoA concentrations on enzyme reaction Escherichia coli ?
-
 ?
2.3.1.51 additional information 1-acyl-sn-glycerol 3-phosphate is readily acylated by unsaturated and saturated acyl-CoAs Escherichia coli ?
-
 ?
2.3.1.51 additional information effect of acyl-CoA concentrations on enzyme reaction Escherichia coli B / ATCC 11303 ?
-
 ?
2.3.1.51 additional information 1-acyl-sn-glycerol 3-phosphate is readily acylated by unsaturated and saturated acyl-CoAs Escherichia coli B / ATCC 11303 ?
-
 ?
2.3.1.51 oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate twice as good as palmitoyl-CoA Escherichia coli CoA + 1-acyl-2-oleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 palmitoyl-CoA + 1-acyl-sn-glycerol 3-phosphate
-
 Escherichia coli CoA + 1-acyl-2-palmitoyl-sn-glycerol 3-phosphate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.51 7.5
-
 assay at Escherichia coli
2.3.1.51 7.5 8
-
 Escherichia coli

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.3.1.51 6.6 8.6 about half-maximal activity at pH 6.6 and 8.6 Escherichia coli