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Literature summary extracted from

  • Lowenson, J.D.; Kim, E.; Young, S.G.; Clarke, S.
    Limited accumulation of damaged proteins in L-isoaspartyl (D-aspartyl) O-methyltransferase-deficient mice (2001), J. Biol. Chem., 276, 20695-20702.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.1.1.77 cytosol
-
 Mus musculus 5829
-
2.1.1.77 cytosol
-
 Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate Mus musculus
-
 S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate Homo sapiens
-
 S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate Xenopus laevis
-
 S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.77 Homo sapiens
-
 human
-
2.1.1.77 Homo sapiens
-
 HeLa cells
-
2.1.1.77 Mus musculus
-
-
-
2.1.1.77 Xenopus laevis
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.77 brain
-
 Mus musculus
-
2.1.1.77 brain
-
 Homo sapiens
-
2.1.1.77 erythrocyte
-
 Mus musculus
-
2.1.1.77 erythrocyte
-
 Homo sapiens
-
2.1.1.77 heart
-
 Mus musculus
-
2.1.1.77 kidney
-
 Mus musculus
-
2.1.1.77 kidney
-
 Homo sapiens
-
2.1.1.77 liver
-
 Mus musculus
-
2.1.1.77 oocyte
-
 Xenopus laevis
-
2.1.1.77 testis
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.77 S-adenosyl-L-methionine + calmodulin
-
 Homo sapiens S-adenosyl-L-homocysteine + ?
-
 ?
2.1.1.77 S-adenosyl-L-methionine + calmodulin
-
 Xenopus laevis S-adenosyl-L-homocysteine + ?
-
 ?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate
-
 Mus musculus S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate
-
 Homo sapiens S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?
2.1.1.77 S-adenosyl-L-methionine + protein L-isoaspartate
-
 Xenopus laevis S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.77 PCMT1
-
 Mus musculus
2.1.1.77 PCMT1
-
 Homo sapiens