Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Zhou, X.; Toney, M.D.
    pH Studies on the mechanism of the pyridoxal phosphate-dependent dialkylglycine decarboxylase (1999), Biochemistry, 38, 311-320.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.64 additional information not inhibitory: pyruvate Burkholderia cepacia

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.64 0.098
-
 pyruvate pH 7.5 Burkholderia cepacia
4.1.1.64 2.2
-
 2-aminoisobutyrate pH 7.5 Burkholderia cepacia

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.64 Burkholderia cepacia
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
4.1.1.64 2,2-dialkylglycine + pyruvate = dialkyl ketone + CO2 + L-alanine mechanism Burkholderia cepacia
a
4.1.1.64 2,2-dialkylglycine + pyruvate = dialkyl ketone + CO2 + L-alanine pH-studies on the mechanism Burkholderia cepacia
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.64 2-aminoisobutyrate + pyruvate
-
 Burkholderia cepacia L-Ala + acetone + CO2
-
 ?
4.1.1.64 Pyruvate + 2-aminoisobutanoate
-
 Burkholderia cepacia ?
-
 ?

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.1.1.64 additional information
-
 pH-dependence of transamination half-reaction Burkholderia cepacia

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.64 pyridoxal 5'-phosphate dependent on Burkholderia cepacia