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Literature summary extracted from

  • Zhu, B.T.; Patel, U.K.; Cai, M.X.; Conney, A.H.
    O-Methylation of tea polyphenols catalyzed by human placental cytosolic catechol-O-methyltransferase (2000), Drug Metab. Dispos., 28, 1024-1030.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.1.6 S-adenosyl-L-homocysteine 50% inhibition at about 0.005 mM Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.1.1.6 0.0022 0.0082 (-)-epicatechin
-
 Homo sapiens
2.1.1.6 0.0039 0.0067 (-)-epigallocatechin
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.6 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.6 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.6 (+)-epicatechin + S-adenosyl-L-methionine
-
 Homo sapiens S-adenosyl-L-homocysteine + ?
-
 ?
2.1.1.6 (-)-epicatechin + S-adenosyl-L-methionine
-
 Homo sapiens S-adenosyl-L-homocysteine + ?
-
 ?
2.1.1.6 (-)-epigallocatechin + S-adenosyl-L-methionine
-
 Homo sapiens S-adenosyl-L-homocysteine + ?
-
 ?