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Literature summary extracted from

  • Sun, I.L.; Toole-Simms, W.; Crane, F.L.; Golub, E.S.; Diaz de Pagan, T.; Morre, D.J.; Löw, H.
    Retinoic acid inhibition of transplasmalemma diferric transferrin reductase (1987), Biochem. Biophys. Res. Commun., 146, 976-982.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.16.1.2 all-trans retinoic acid
-
 Homo sapiens
1.16.1.2 all-trans retinoic acid
-
 Rattus norvegicus
1.16.1.2 additional information retinol and retinyl acetate have very little inhibitory effect Homo sapiens
1.16.1.2 additional information
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.16.1.2 cytoplasmic membrane
-
 Homo sapiens
-
-
1.16.1.2 cytoplasmic membrane
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.16.1.2 Homo sapiens
-
-
-
1.16.1.2 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.16.1.2 HeLa cell
-
 Homo sapiens
-
1.16.1.2 liver
-
 Homo sapiens
-
1.16.1.2 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.16.1.2 ferritin[Fe(III)] + NADH
-
 Homo sapiens ferritin[Fe(II)] + NAD+
-
 ?
1.16.1.2 ferritin[Fe(III)] + NADH
-
 Rattus norvegicus ferritin[Fe(II)] + NAD+
-
 ?
1.16.1.2 transferrin[Fe(III)]2 + NADH
-
 Homo sapiens transferrin[Fe(II)]2 + NAD+
-
 ?
1.16.1.2 transferrin[Fe(III)]2 + NADH
-
 Rattus norvegicus transferrin[Fe(II)]2 + NAD+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.16.1.2 NADH
-
 Homo sapiens
1.16.1.2 NADH
-
 Rattus norvegicus