Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Zhang, J.; Demain, A.L.
    Regulation of ACV synthetase activity in the beta-lactam biosynthetic pathway by carbon sources and their metabolites (1992), Arch. Microbiol., 158, 364-369.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.2.26 D-glucose crude extract is inhibited due to deprivation of ATP via sugar metabolism Acremonium chrysogenum
6.3.2.26 glyceraldehyde
-
 Acremonium chrysogenum
6.3.2.26 glyceraldehyde
-
 Streptomyces clavuligerus
6.3.2.26 glyceraldehyde-3-phosphate reacts with L-cysteinee Acremonium chrysogenum
6.3.2.26 glyceraldehyde-3-phosphate reacts with L-cysteinee Streptomyces clavuligerus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.3.2.26 Mg2+
-
 Acremonium chrysogenum
6.3.2.26 Mg2+
-
 Streptomyces clavuligerus

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.26 Acremonium chrysogenum
-
-
-
6.3.2.26 Streptomyces clavuligerus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.26 L-2-aminoadipate + L-cysteine + L-valine + ATP
-
 Acremonium chrysogenum N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine + AMP + diphosphate
-
 ?
6.3.2.26 L-2-aminoadipate + L-cysteine + L-valine + ATP
-
 Streptomyces clavuligerus N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine + AMP + diphosphate
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
6.3.2.26 ATP
-
 Acremonium chrysogenum
6.3.2.26 ATP
-
 Streptomyces clavuligerus